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Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN
- Arnoult, Nausica;
- Correia, Adriana;
- Ma, Jiao;
- Merlo, Anna;
- Garcia-Gomez, Sara;
- Maric, Marija;
- Tognetti, Marco;
- Benner, Christopher W;
- Boulton, Simon J;
- Saghatelian, Alan;
- Karlseder, Jan
Published Web Location
https://doi.org/10.1038/nature24023Abstract
CYREN is a direct inhibitor of classical non-homologous end joining that promotes error-free repair by homologous recombination during the S and G2 phases of the cell cycle.
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