Skip to main content
eScholarship
Open Access Publications from the University of California

In vivo infrared tomographic imaging of laser-heated blood vessels

  • Author(s): Telenkov, SA
  • Tanenbaum, BS
  • Goodman, DM
  • Nelson, JS
  • Milner, TE
  • et al.
Abstract

We demonstrate a method for infrared tomographic imaging of the initial three-dimensional (3-D) temperature increase of in vivo blood vessels following pulsed laser exposure. Using a time-sequence of infrared images recorded by a fast focal plane array camera as input data, a reconstruction algorithm is used to compute the initial 3-D temperature increases in the chick chorioallantoic membrane and port wine stain in human skin. The noncontact tomographic imaging method is relevant to various laser therapies that rely on a photothermal mechanism for selective modification of tissue and may find diagnostic application to determine optimal laser dosimetry, position, and size of targeted subsurface chromophores.

Many UC-authored scholarly publications are freely available on this site because of the UC Academic Senate's Open Access Policy. Let us know how this access is important for you.

Main Content
Current View