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Muscle Development: Nucleating Microtubules at the Nuclear Envelope
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https://doi.org/10.1016/j.cub.2017.08.030Abstract
Microtubule-organizing centers move from centrosomes to the nuclear envelope during muscle development. The KASH protein Nesprin-1α recruits pericentriolar material to the surface of myotube nuclei, where it nucleates microtubules to ensure even spacing of nuclei within the developing myotube.
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