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Vasoconstrictory effects of adrenalin on the perfused head of the eel (Anguilla angvilla L.)

  • Author(s): Pinto, A
  • Piomelli, D
  • et al.
Abstract

1. 1. Adrenalin (5.0 × 10-5M) increases gill vascular resistance up to 23.2 ± 6.8% in the isolated and perfused head of the european eel (Anguilla anguilla L.). 2. 2. This vasoactive response is nearly abolished by the α-adrenergic blocking agent phentolamine mesylate (5.0 × 10-4M), while it is increased by the β-blocker propranolol (5.0 × 10-5M). 3. 3. From these results it may be inferred that, in our experimental conditions, the major response to the catecholamine is a vasoconstriction mediated via α-adrenoceptors. © 1983.

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