Vasoconstrictory effects of adrenalin on the perfused head of the eel (Anguilla anguilla L.).
- Author(s): Pinto, A;
- Piomelli, D
- et al.
Published Web Locationhttps://doi.org/10.1016/0742-8413(83)90065-8
Adrenalin (5.0 X 10(-5) M) increases gill vascular resistance up to 23.2 +/- 6.8% in the isolated and perfused head of the european eel (Anguilla anguilla L.). This vasoactive response is nearly abolished by the alpha-adrenergic blocking agent phentolamine mesylate (5.0 X 10(-5) M), while it is increased by the beta-blocker propranolol (5.0 X 10(-4) M). From these results it may be inferred that, in our experimental conditions, the major response to the catecholamine is a vasoconstriction mediated via alpha-adrenoceptors.