Skip to main content
Open Access Publications from the University of California

18Fluorodeoxyglucose PET in schizophrenia

  • Author(s): Jernigan, TL
  • Sargent, T
  • Pfefferbaum, A
  • Kusubov, N
  • Stahl, SM
  • et al.

Six chronic schizophrenic patients and six age-matched controls were studied with18fluorodeoxyglucose (18FDG) positron emission tomography (PET). All patients were scanned when they had been free of medication for at least 2 weeks. Comparisons were made between the groups on regional ratios of cortical18FDG, with manual and automated measures. Only one of eight regions, the right temporal cortical region, showed a significant group difference, and this effect was not significant when adjustment was made for multiple comparisons. Secondary analyses suggest that ventricular enlargement and age may be associated with a relatively "hypofrontal" pattern of18FDG. © 1985.

Many UC-authored scholarly publications are freely available on this site because of the UC Academic Senate's Open Access Policy. Let us know how this access is important for you.

Main Content
Current View