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Quantifying metabolic heterogeneity in head and neck tumors in real time: 2-DG uptake is highest in hypoxic tumor regions

  • Author(s): Grandis, Jennifer
  • Nakajima, EC
  • Laymon, C
  • Oborski, M
  • Hou, W
  • Wang, L
  • Grandis, JR
  • Ferris, RL
  • Mountz, JM
  • Van, B
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4134191?pdf=render
No data is associated with this publication.
Abstract

Purpose: Intratumoral metabolic heterogeneity may increase the likelihood of treatment failure due to the presence of a subset of resistant tumor cells. Using a head and neck squamous cell carcinoma (HNSCC) xenograft model and a real-time fluorescence imag

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