Skip to main content
eScholarship
Open Access Publications from the University of California

UCLA

UCLA Previously Published Works bannerUCLA

An inhibitory pull–push circuit in frontal cortex

Abstract

Using large-network calcium imaging in alert mouse frontal cortex, the authors identify a significant covariance of responses of VIP interneurons and pyramidal cells. Optogenetic interrogation of this brain region revealed a pull–push inhibitory circuit driven by neuromodulation of VIP interneurons that contrasts with canonical feedforward push–pull excitation.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.