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Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

  • Author(s): Finkbeiner, Steven
  • Barmada, SJ
  • Serio, A
  • Arjun, A
  • Bilican, B
  • Daub, A
  • Ando, DM
  • Tsvetkov, A
  • Pleiss, M
  • Li, X
  • Peisach, D
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4106236?pdf=render
No data is associated with this publication.
Abstract

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) have distinct clinical features but a common pathology-cytoplasmic inclusions rich in transactive response element DNA-binding protein of 43 kDa (TDP43). Rare TDP43 mutations cause ALS o

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