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Open Access Publications from the University of California

Biochemical and biophysical characterization of cell-free synthesized Rift Valley fever virus nucleoprotein capsids enables in vitro screening to identify novel antivirals.

  • Author(s): Lingappa, Vishwanath
  • Broce, S
  • Hensley, L
  • Sato, T
  • Lehrer-Graiwer, J
  • Essrich, C
  • Edwards, KJ
  • Pajda, J
  • Davis, CJ
  • Bhadresh, R
  • Hurt, CR
  • et al.

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Viral capsid assembly involves the oligomerization of the capsid nucleoprotein (NP), which is an essential step in viral replication and may represent a potential antiviral target. An in vitro transcription-translation reaction using a wheat germ (WG) extr

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