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Biochemical and biophysical characterization of cell-free synthesized Rift Valley fever virus nucleoprotein capsids enables in vitro screening to identify novel antivirals.

  • Author(s): Lingappa, Vishwanath
  • Broce, S
  • Hensley, L
  • Sato, T
  • Lehrer-Graiwer, J
  • Essrich, C
  • Edwards, KJ
  • Pajda, J
  • Davis, CJ
  • Bhadresh, R
  • Hurt, CR
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4867995?pdf=render
No data is associated with this publication.
Abstract

Viral capsid assembly involves the oligomerization of the capsid nucleoprotein (NP), which is an essential step in viral replication and may represent a potential antiviral target. An in vitro transcription-translation reaction using a wheat germ (WG) extr

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