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Open Access Publications from the University of California

Crystal structure of an amphiphilic foldamer reveals a 48-mer assembly comprising a hollow truncated octahedron

  • Author(s): Degrado, William
  • Pavone, V
  • Zhang, SQ
  • Merlino, A
  • Lombardi, A
  • Wu, Y
  • DeGrado, WF
  • et al.

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Foldamers provide an attractive medium to test the mechanisms by which biological macromolecules fold into complex three-dimensional structures, and ultimately to design novel protein-like architectures with properties unprecedented in nature. Here, we des

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