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Open Access Publications from the University of California

Monoclonal antibodies that inhibit the proteolytic activity of botulinum neurotoxin serotype/B

  • Author(s): Marks, James
  • Fan, Y
  • Dong, J
  • Lou, J
  • Wen, W
  • Conrad, F
  • Geren, IN
  • Garcia-Rodriguez, C
  • Smith, TJ
  • Smith, LA
  • Ho, M
  • et al.

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.Existing antibodies (Abs) used to treat botulism cannot enter the cytosol of neurons and bind to botulinum neurotoxin (BoNT) at its site of action, and thus cannot reverse paralysis. However, Abs tar

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