UCSF

To determine how the intersection of increased urban growth and poverty has impacted HIV incidence and prevalence, given growing HIV inequalities globally. Retrospective analysis using combined data from five publicly available, population-level datasets to determine city- and within-urban countrywide estimates of 95-95-95 treatment targets, prevalence and incidence rates from 2015 to 2019. For city-level estimates, we analysed combined data from: Fast-Track City (FTC), SINAN from Brazil and UNAIDS Naomi-Spectrum. Countrywide estimates of HIV prevalence in the urban slum versus non-slum since 2012 were compiled from Population-Based HIV Impact Assessment (PHIA) surveys in 12 countries and Demographic Health Surveys (DHS) in 28 countries. HIV prevalence is generally higher among the urban slum, compared to their non-slum counterparts, thus resulting in national HIV estimates masking nuances in HIV inequalities between the urban slum and non-slum. Specifically, national and city-level HIV estimates mask inequalities within and between cities, with secondary cities often having higher HIV prevalence and incidence rates than capital cities and large urban areas. The urban divide between slum and non-slum populations is a contributor to HIV inequality, often with poorer outcomes in smaller cities than their larger counterparts. Interventions tailored to cities, and particularly those considering local nuances in subpopulations (eg, different genders, ages, roles), are necessary to reduce HIV inequality. Focused HIV programming accounting for structural drivers of inequalities between urban slum and non-slum populations such as inequalities in wealth, education, employment and housing are crucial to closing gaps driving HIV inequalities globally.