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Astrocytes Underlie Neuroinflammatory Memory Impairment.

  • Author(s): Osso, Lindsay A
  • Chan, Jonah R
  • et al.
Abstract

Neuroinflammation is being increasingly recognized as a potential mediator of cognitive impairments in various neurological conditions. Habbas et al. demonstrate that the pro-inflammatory cytokine tumor necrosis factor alpha signals through astrocytes to alter synaptic transmission and impair cognition in a mouse model of multiple sclerosis.

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