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Astrocytes Underlie Neuroinflammatory Memory Impairment
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https://doi.org/10.1016/j.cell.2015.12.001Abstract
Neuroinflammation is being increasingly recognized as a potential mediator of cognitive impairments in various neurological conditions. Habbas et al. demonstrate that the pro-inflammatory cytokine tumor necrosis factor alpha signals through astrocytes to alter synaptic transmission and impair cognition in a mouse model of multiple sclerosis.
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