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A Biomimetic Synthesis of des-Hydroxy Paecilospirone

  • Author(s): Feng, Zhen-Gao;
  • Burnett, G Leslie;
  • Pettus, Thomas RR
  • et al.
Abstract

The carbon framework of des-hydroxy paecilospirone was rapidly synthesized using a biomimetic approach whereby an enol ether and an ortho-quinone methide (o-QM), each derived from the same lactone, were combined to arrive at the complete carbon skeleton of paecilospirone.

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