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Complexities of TGF-β targeted cancer therapy.
Published Web Location
http://europepmc.org/articles/PMC3399319?pdf=renderNo data is associated with this publication.
Abstract
Many advanced tumors produce excessive amounts of Transforming Growth Factor-β (TGF-β) which, in normal epithelial cells, is a potent growth inhibitor. However, in oncogenically activated cells, the homeostatic action of TGF-β is often diverted along alter
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