A pharmacological organization of G protein-coupled receptors
- Author(s): Shoichet, Brian
- Lin, H
- Sassano, MF
- Roth, BL
- Shoichet, BK
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3560304?pdf=render
Protein classification typically uses structural, sequence or functional similarity. Here we introduce an orthogonal method that organizes proteins by ligand similarity, focusing on the class A G-protein-coupled receptor (GPCR) protein family. Comparing a
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