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Resistance is futile.

  • Author(s): Semler, Bert L
  • et al.

Published Web Location

https://www.nature.com/articles/ng0705-665
No data is associated with this publication.
Abstract

A new study of dominant negative functions in cells infected by a positive-strand RNA virus detects an array of locus- and allele-specific effects. Exploiting subunit defects in multi-component complex assemblies provides a new approach to identifying targets for antiviral therapies that may inhibit the emergence of drug-resistant RNA virus populations.

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