B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity
- Author(s): Zamvil, Scott
- Lehmann-Horn, K
- Sagan, SA
- Bernard, CCA
- Sobel, RA
- Zamvil, SS
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC4405474?pdf=render
© 2015 The Authors Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association.Natalizumab, which binds very late antigen-4 (VLA-4), is a potent therapy for multiple sclerosis (MS). Studies have focused primarily
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