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HIV-1 persistence in CD4+ T cells with stem cell-like properties.

  • Author(s): Henrich, Timothy
  • Buzon, MJ
  • Sun, H
  • Li, C
  • Shaw, A
  • Seiss, K
  • Ouyang, Z
  • Martin-Gayo, E
  • Leng, J
  • Henrich, TJ
  • Li, JZ
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3959167?pdf=render
No data is associated with this publication.
Abstract

Cellular HIV-1 reservoirs that persist despite antiretroviral treatment are incompletely defined. We show that during suppressive antiretroviral therapy, CD4(+) T memory stem cells (TSCM cells) harbor high per-cell levels of HIV-1 DNA and make increasing c

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