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Interferon-β–Induced Pulmonary Arterial Hypertension Approach to Diagnosis and Clinical Monitoring
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https://doi.org/10.1016/j.jaccas.2021.02.005Abstract
A 48-year-old woman who had been receiving long-term interferon-β for 8 years for multiple sclerosis developed drug-induced World Health Organization group I pulmonary arterial hypertension. Triple therapy for pulmonary arterial hypertension and suspension of interferon-β led to improvement from a high-risk to low-risk state and improvement in exercise hemodynamics, including vascular distensibility, and right ventricle-pulmonary artery coupling. (Level of Difficulty: Advanced.).
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