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Th1 cell induction in lymph nodes according to a red-blue chemokine map.
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https://doi.org/10.1016/j.immuni.2012.11.007Abstract
Lymph nodes are compartmentalized organs but whether this feature has a role in T cell differentiation has been unclear. In this issue, Groom et al. (2012) reveal that spatially separated expression of two CXCR3 ligands guides Th1 cell development.
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