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A role for external Ca2+ in maintaining muscle contractility in periodic paralysis.
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https://doi.org/10.1085/jgp.202012615Abstract
Calcium gluconate has been empirically administered to hasten recovery of force during an episode of periodic paralysis. By using a genetically engineered mouse model, Uwera and colleagues show that low Ca2+ clearly promotes a loss of force in affected muscle, thereby providing the first evidence for the benefit of maintaining normal Ca2+ levels in this disorder.
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