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Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

Published Web Location

http://europepmc.org/articles/PMC4406054?pdf=render
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Abstract

© 2015 Macmillan Publishers Limited.Despite antiretroviral therapy (ART),humanimmunodeficiency virus (HIV)-1 persists in a stable latent reservoir1,2, primarily in resting memory CD41 T cells3,4. This reservoir presents a major barrier to the cure of HIV-1

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