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Hot topic in optogenetics: new implications of in vivo tissue heating
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https://doi.org/10.1038/s41593-019-0426-zAbstract
In this issue of Nature Neuroscience, Owen et al. show that widely used optogenetic light delivery can heat brain tissue and produce changes in neural activity and behavior in the absence of opsins. How will this finding influence experimental design in the optical age of neuroscience?
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