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Fixing the leak: targeting the vascular endothelium in sepsis
Published Web Location
http://europepmc.org/articles/PMC3672578?pdf=renderNo data is associated with this publication.
Abstract
Angiopoietin-1 is a Tie-2 receptor agonist that stabilizes vascular endothelium, promoting endothelial maturation and preventing capillary leak. Angiopoietin-2 is largely a competitive partial antagonist that is markedly elevated in humans and animal model
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