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Dual kinase-bromodomain inhibitors for rationally designed polypharmacology
Published Web Location
http://europepmc.org/articles/PMC3998711?pdf=renderNo data is associated with this publication.
Abstract
Concomitant inhibition of multiple cancer-driving kinases is an established strategy to improve the durability of clinical responses to targeted therapies. The difficulty of discovering kinase inhibitors with an appropriate multitarget profile has, however
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