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Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures

  • Author(s): Wiemels, Joseph
  • Wiencke, John
  • Wrensch, Margaret
  • Lee, ST
  • Muench, MO
  • Fomin, ME
  • Xiao, J
  • Zhou, M
  • De, A
  • Martín-Subero, JI
  • Heath, S
  • Houseman, EA
  • Roy, R
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4357708?pdf=render
No data is associated with this publication.
Abstract

© The Author(s) 2015.We investigated DNA methylomes of pediatric Bcell acute lymphoblastic leukemias (B-ALLs) using whole-genome bisulfite sequencing and highdefinition microarrays, along with RNA expression profiles. Epigenetic alteration of B-ALLs occurr

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