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Identification of a rare coding variant in complement 3 associated with age-related macular degeneration

  • Author(s): Gorin, Michael
  • Moore, Anthony
  • Zhan, X
  • Larson, DE
  • Wang, C
  • Koboldt, DC
  • Sergeev, YV
  • Fulton, RS
  • Fulton, LL
  • Fronick, CC
  • Branham, KE
  • Bragg-Gresham, J
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3812337?pdf=render
No data is associated with this publication.
Abstract

Macular degeneration is a common cause of blindness in the elderly. To identify rare coding variants associated with a large increase in risk of age-related macular degeneration (AMD), we sequenced 2,335 cases and 789 controls in 10 candidate loci (57 gene

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