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Downregulation of MYCN through PI3K inhibition in mouse models of pediatric neural cancer

  • Author(s): Gustafson, William
  • Cage, TA
  • Chanthery, Y
  • Chesler, L
  • Grimmer, M
  • Knight, Z
  • Shokat, K
  • Weiss, WA
  • Gustafson, WC
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4429235?pdf=render
No data is associated with this publication.
Abstract

© 2015 Cage, Chanthery, Chesler, Grimmer, Knight, Shokat, Weiss and Gustafson.The MYCN proto-oncogene is associated with poor outcome across a broad range of pediatric tumors. While amplification of MYCN drives subsets of high-risk neuroblastoma and medull

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