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Downregulation of MYCN through PI3K inhibition in mouse models of pediatric neural cancer

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© 2015 Cage, Chanthery, Chesler, Grimmer, Knight, Shokat, Weiss and Gustafson.The MYCN proto-oncogene is associated with poor outcome across a broad range of pediatric tumors. While amplification of MYCN drives subsets of high-risk neuroblastoma and medull

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