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ECM-Dependent HIF Induction Directs Trophoblast Stem Cell Fate via LIMK1-Mediated Cytoskeletal Rearrangement

  • Author(s): Maltepe, Emin
  • Rinaudo, Paolo
  • Choi, HJ
  • Sanders, TA
  • Tormos, KV
  • Ameri, K
  • Tsai, JD
  • Park, AM
  • Gonzalez, J
  • Rajah, AM
  • Liu, X
  • Quinonez, DM
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3578927?pdf=render
No data is associated with this publication.
Abstract

The Hypoxia-inducible Factor (HIF) family of transcriptional regulators coordinates the expression of dozens of genes in response to oxygen deprivation. Mammalian development occurs in a hypoxic environment and HIF-null mice therefore die in utero due to m

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