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Therapeutic Helminth Infection of Macaques with Idiopathic Chronic Diarrhea Alters the Inflammatory Signature and Mucosal Microbiota of the Colon

  • Author(s): McCune, Joseph
  • Kim, Charles
  • Broadhurst, MJ
  • Ardeshir, A
  • Kanwar, B
  • Mirpuri, J
  • Gundra, UM
  • Leung, JM
  • Wiens, KE
  • Vujkovic-Cvijin, I
  • Kim, CC
  • Yarovinsky, F
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3499566?pdf=render
No data is associated with this publication.
Abstract

Idiopathic chronic diarrhea (ICD) is a leading cause of morbidity amongst rhesus monkeys kept in captivity. Here, we show that exposure of affected animals to the whipworm Trichuris trichiura led to clinical improvement in fecal consistency, accompanied by

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