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Field Performance and Public Health Response Using the BinaxNOWTM Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing.

  • Author(s): Pilarowski, Genay;
  • Marquez, Carina;
  • Rubio, Luis;
  • Peng, James;
  • Martinez, Jackie;
  • Black, Douglas;
  • Chamie, Gabriel;
  • Jones, Diane;
  • Jacobo, Jon;
  • Tulier-Laiwa, Valerie;
  • Rojas, Susana;
  • Rojas, Susy;
  • Cox, Chesa;
  • Nakamura, Robert;
  • Petersen, Maya;
  • DeRisi, Joseph;
  • Havlir, Diane V
  • et al.
Abstract

Among 3302 persons tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by BinaxNOWTM and reverse transcription polymerase chain reaction (RT-PCR) in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR cycle thresholds of 30, 35, and no threshold. The specificity was 99.9%. Performance was high across ages and those with and without symptoms. Rapid resulting permitted immediate public health action.

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