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Hypoxic preconditioning protection is eliminated in HIF-1 αknockout mice subjected to neonatal hypoxia ischemia

  • Author(s): Ferriero, Donna
  • Ann, R
  • Lee, CL
  • Jiang, X
  • Knox, RN
  • Ferriero, DM
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4167022?pdf=render
No data is associated with this publication.
Abstract

Background:Hypoxic preconditioning (HPc) protects the neonatal brain in the setting of hypoxia-ischemia (HI). The mechanisms of protection may depend on activation of hypoxia-inducible factor (HIF-1). This study sought to clarify the role of HIF-1 after HP

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