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Hypoxic preconditioning protection is eliminated in HIF-1 αknockout mice subjected to neonatal hypoxia ischemia

Published Web Location

http://europepmc.org/articles/PMC4167022?pdf=render
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Abstract

Background:Hypoxic preconditioning (HPc) protects the neonatal brain in the setting of hypoxia-ischemia (HI). The mechanisms of protection may depend on activation of hypoxia-inducible factor (HIF-1). This study sought to clarify the role of HIF-1 after HP

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