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The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors
- Lefrançais, Emma;
- Ortiz-Muñoz, Guadalupe;
- Caudrillier, Axelle;
- Mallavia, Beñat;
- Liu, Fengchun;
- Sayah, David M;
- Thornton, Emily E;
- Headley, Mark B;
- David, Tovo;
- Coughlin, Shaun R;
- Krummel, Matthew F;
- Leavitt, Andrew D;
- Passegué, Emmanuelle;
- Looney, Mark R
Published Web Location
https://doi.org/10.1038/nature21706Abstract
Direct imaging of the lung microcirculation in mice indicates that it is a major site of mature platelet production from megakaryocytes.
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