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Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair

  • Author(s): Bikle, Daniel
  • Yoshizaki, K
  • Hu, L
  • Nguyen, T
  • Sakai, K
  • He, B
  • Fong, C
  • Yamada, Y
  • Bikle, DD
  • Oda, Y
  • et al.

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Cell fates are determined by specific transcriptional programs. Here we provide evidence that the transcriptional coactivator, Mediator 1 (Med1), is essential for the cell fate determination of ectodermal epithelia. Conditional deletion of Med1 in vivo con

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