Skip to main content
Open Access Publications from the University of California

3D nanometer images of biological fibers by directed motion of gold nanoparticles.

  • Author(s): Estrada, Laura C
  • Gratton, Enrico
  • et al.

Published Web Location Commons 'BY' version 4.0 license

Using near-infrared femtosecond pulses, we move single gold nanoparticles (AuNPs) along biological fibers, such as collagen and actin filaments. While the AuNP is sliding on the fiber, its trajectory is measured in three dimensions (3D) with nanometer resolution providing a high-resolution image of the fiber. Here, we systematically moved a single AuNP along nanometer-size collagen fibers and actin filament inside chinese hamster ovary K1 living cells, mapping their 3D topography with high fidelity.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content
Current View