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Open Access Publications from the University of California

Role of antiplatelet therapy in cardiovascular disease II: Ischemic stroke.

  • Author(s): Cavendish, Jeffrey J
  • Cramer, Steven C
  • Graham, Glenn D
  • et al.

The etiology of cerebrovascular disease is heterogeneous, with the majority of strokes being of ischemic origin. Transient ischemic attack is now considered to be an important precursor and long-term risk factor for ischemic stroke. Given the lack of acute therapies for ischemic stroke, current treatments focus on secondary prevention through risk-factor management, pharmacotherapy and interventional approaches. As illustrated in this paper, antiplatelet agents (e.g. clopidogrel, aspirin, dipyridamole) are the cornerstone of therapy for prevention of recurrent ischemic stroke.

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