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Design limitations of a photoacoustic probe for port wine stain depth determination
Abstract
We designed a photoacoustic probe to determine the depths of epidermal melanin layer and port wine stain (PWS) in human skin. We present experimental data showing limitations in its use. We developed acrylamide tissue phantoms with optical properties matched to those of human PWS skin. We determined the limit in resolving epidermal and PWS layers. Additionally, we determined the maximum epidermal melanin concentration that allowed threshold detection of the PWS layer. Finally, we compared the photoacoustic signals from the tissue phantoms and human PWS skin.
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