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Effectiveness of Nonadjuvanted Monovalent Influenza A(H1N1)pdm09 Vaccines for Preventing Reverse Transcription Polymerase Chain Reaction–Confirmed Pandemic Influenza Hospitalizations: Case-Control Study of Children and Adults at 10 US Influenza Surveillance Network Sites
- Thompson, Mark G;
- Sokolow, Leslie Z;
- Almendares, Olivia;
- Openo, Kyle;
- Farley, Monica M;
- Meek, James;
- Ray, Julie;
- Kirley, Pamala Daily;
- Reingold, Arthur;
- Aragon, Deborah;
- Hancock, Emily;
- Baumbach, Joan;
- Schaffner, William;
- Thomas, Ann;
- Lynfield, Ruth;
- Ryan, Pat;
- Monroe, Maya;
- Cheng, Po-Yung;
- Fry, Alicia M;
- Shay, David K
- et al.
Published Web Location
https://doi.org/10.1093/cid/cit551Abstract
During 2009-2010, we examined 217 patients hospitalized with laboratory-confirmed pandemic influenza in 9 Influenza Hospitalization Surveillance Network sites and 413 age- and community-matched controls and found that a single dose of monovalent nonadjuvanted influenza A(H1N1)pdm09 vaccine was 50% (95% confidence interval, 13%-71%) effective in preventing hospitalization associated with A(H1N1)pdm09 virus infection.
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