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Open Access Publications from the University of California

Loss of a Neural AMP-Activated Kinase Mimics the Effects of Elevated Serotonin on Fat, Movement, and Hormonal Secretions

  • Author(s): Ashrafi, Kaveh
  • Cunningham, KA
  • Bouagnon, AD
  • Barros, AG
  • Lin, L
  • Malard, L
  • Romano-Silva, MA
  • et al.

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AMP-activated protein kinase (AMPK) is an evolutionarily conserved master regulator of metabolism and a therapeutic target in type 2 diabetes. As an energy sensor, AMPK activity is responsive to both metabolic inputs, for instance the ratio of AMP to ATP,

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