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Automated whole-genome multiple alignment of rat, mouse, and human

2004

Brudno, Michael;
Poliakov, Alexander;
Salamov, Asaf;
Cooper, Gregory M.;
Sidow, Arend;
Rubin, Edward M.;
Solovyev, Victor;
Batzoglou, Serafim;
Dubchak, Inna
et al.

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Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human
RESULTS
Overview of strategy for multiple alignment of the human, mouse, and rat genomes
Exon–based map of conserved synteny among the thr
Evaluation of the quality of three-way alignments
Agreement between alignments and the exon--based map
Multi-VISTA Browser
METHODS
Progressive alignment strategy
Implementation
Multi-VISTA Browser, accessible at http://pipeline.lbl.gov, is a Java 2 applet that can display multiple human-mouse-rat alignments along with genome annotations using any of the three species as a reference (coordinate) sequence. Its graphical user in
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