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Open Access Publications from the University of California

Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells

  • Author(s): Kriegstein, Arnold
  • Hsiao, Edward
  • Weiss, Lauren
  • Bershteyn, M
  • Hayashi, Y
  • Desachy, G
  • Hsiao, EC
  • Sami, S
  • Tsang, KM
  • Yamanaka, S
  • Wynshaw-Boris, A
  • et al.

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Ring chromosomes are structural aberrations commonly associated with birth defects, mental disabilities and growth retardation. Rings form after fusion of the long and short arms of a chromosome, and are sometimes associated with large terminal deletions.

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