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Negative regulation of Hif1a expression and TH 17 differentiation by the hypoxia-regulated microRNA miR-210

  • Author(s): Weiss, Arthur
  • McManus, Thomas
  • Wang, H
  • Flach, H
  • Onizawa, M
  • Wei, L
  • Mcmanus, MT
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3996831?pdf=render
No data is associated with this publication.
Abstract

The microRNA miR-210 is a signature of hypoxia. We found robust increase in the abundance of miR-210 (>100-fold) in activated T cells, especially in the T H 17 lineage of helper T cells. Hypoxia acted in synergy with stimulation via the T cell antigen rece

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