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Negative regulation of Hif1a expression and TH 17 differentiation by the hypoxia-regulated microRNA miR-210

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The microRNA miR-210 is a signature of hypoxia. We found robust increase in the abundance of miR-210 (>100-fold) in activated T cells, especially in the T H 17 lineage of helper T cells. Hypoxia acted in synergy with stimulation via the T cell antigen rece

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