Negative regulation of Hif1a expression and TH 17 differentiation by the hypoxia-regulated microRNA miR-210
- Author(s): Weiss, Arthur
- McManus, Thomas
- Wang, H
- Flach, H
- Onizawa, M
- Wei, L
- Mcmanus, MT
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3996831?pdf=render
The microRNA miR-210 is a signature of hypoxia. We found robust increase in the abundance of miR-210 (>100-fold) in activated T cells, especially in the T H 17 lineage of helper T cells. Hypoxia acted in synergy with stimulation via the T cell antigen rece
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