tsRNAs: new players in mammalian retrotransposon control.
- Author(s): Zhang, Yunfang
- Shi, Junchao
- Chen, Qi
- et al.
Published Web Locationhttps://doi.org/10.1038/cr.2017.109
A recent study led by Professor Rob Martienssen in Cell showed that 3'-tRNA-derived small RNAs can suppress long terminal repeat retrotransposon activity in mammalian cells by mechanisms independent of DNA-associated epigenetic marks, suggesting how the genome may defend itself from retrotransposon invasion during epigenetic reprogramming.