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Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6
Published Web Location
http://europepmc.org/articles/PMC3515450?pdf=renderNo data is associated with this publication.
Abstract
Inhibition of caspase-6 is a potential therapeutic strategy for some neurodegenerative diseases, but it has been difficult to develop selective inhibitors against caspases. We report the discovery and characterization of a potent inhibitor of caspase-6 tha
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