Clinical Practice and Cases in Emergency Medicine
Administration of Nebulized Ketamine for Managing Acute Pain in the Emergency Department: A Case Series
- Author(s): Drapkin, Jefferson
- Masoudi, Aidin
- Butt, Mahlaqa
- Hossain, Rukhsana
- Likourezos, Antonios
- Motov, Sergey
- et al.
Published Web Locationhttps://doi.org/10.5811/cpcem.2019.10.44582
Ketamine administration in sub-dissociative doses in the emergency department (ED) results in effective pain relief in patients with acute traumatic and non-traumatic pain, chronic pain, and opioid-tolerant pain. This case series describes five adult ED patients who received nebulized ketamine for predominantly acute traumatic pain. Three patients received nebulized ketamine at 1.5 milligrams per kilogram (mg /kg) dose, one patient at 0.75 mg/kg, and one patient at 1 mg/kg. All five patients experienced a decrease in pain from the baseline up to 120 minutes. The inhalation route of ketamine delivery via breath-actuated nebulizer may have utility for managing pain in the ED.