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T cell activation induces proteasomal degradation of argonaute and rapid remodeling of the microRNA repertoire

  • Author(s): Erle, David
  • Ansel, Karl
  • McManus, Thomas
  • Bronevetsky, Y
  • Villarino, AV
  • Eisley, CJ
  • Barbeau, R
  • Barczak, AJ
  • Heinz, GA
  • Kremmer, E
  • Heissmeyer, V
  • McManus, MT
  • Erle, DJ
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3570096?pdf=render
No data is associated with this publication.
Abstract

Activation induces extensive changes in the gene expression program of naive CD4+ T cells, promoting their differentiation into helper T cells that coordinate immune responses. MicroRNAs (miRNAs) play a critical role in this process, and miRNA expression a

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