Elimination of Von Hippel-Lindau Function Perturbs Pancreas Endocrine Homeostasis in Mice
- Author(s): Hebrok, Matthias
- Puri, S
- García-Núñez, A
- Cano, DA
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3748057?pdf=render
Mutations in the human homolog of the Vhlh gene [encoding the von-Hippel Lindau (VHL) protein] lead to tumor development. In mice, depletion of Vhlh in pancreatic ß-cells causes perturbed glucose homeostasis, but the role of this gene in other pancreatic c
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