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Elimination of Von Hippel-Lindau Function Perturbs Pancreas Endocrine Homeostasis in Mice
Published Web Location
http://europepmc.org/articles/PMC3748057?pdf=renderNo data is associated with this publication.
Abstract
Mutations in the human homolog of the Vhlh gene [encoding the von-Hippel Lindau (VHL) protein] lead to tumor development. In mice, depletion of Vhlh in pancreatic ß-cells causes perturbed glucose homeostasis, but the role of this gene in other pancreatic c
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