UC San Diego
The total synthesis and manipulations of norcembrenolides
- Author(s): Sullivan, Steven D. E.
- Sullivan, Steven D. E.
- et al.
Two natural products, norcembrenolide B and scabrolide D, have been synthesized in a biomimetic fashion. With the synthesis, a strategy has been developed for the transformation of furanocembrenolides to their [Beta]- ketotetrahydrofuranone derivatives. Further manipulations, namely C11 and C13 oxidation strategies, have been developed to allow access several natural products of this family