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Open Access Publications from the University of California

The total synthesis and manipulations of norcembrenolides

  • Author(s): Sullivan, Steven D. E.
  • Sullivan, Steven D. E.
  • et al.

Two natural products, norcembrenolide B and scabrolide D, have been synthesized in a biomimetic fashion. With the synthesis, a strategy has been developed for the transformation of furanocembrenolides to their [Beta]- ketotetrahydrofuranone derivatives. Further manipulations, namely C11 and C13 oxidation strategies, have been developed to allow access several natural products of this family

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