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Specific aromatic foldamers potently inhibit spontaneous and seeded Aβ42 and Aβ43 fibril assembly

Published Web Location

http://europepmc.org/articles/PMC4209162?pdf=render
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Abstract

© The Authors Journal compilation © 2014 Biochemical Society.Amyloid fibrils are self-propagating entities that spread pathology in several devastating disorders including Alzheimer's disease (AD). In AD, amyloid-β (Aβ) peptides form extracellular plaques

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